How to maintain freeze dryer lyophilizers?

How to maintain freeze dryer lyophilizers?

Lubricate oil replacement:


  • Regular replace vacuum pump oil.

First time: 500hrs running.

Successive: every 3000hrs.


  • Regular replace compressor oil.

For semi-hermetic compressors.

First time: 2000hrs.

Successive: every 10000hrs.



  1. The labels on vacuum pumps and compressors have guidance of the replacement cycle.
  2. Operator need do daily, weekly and monthly check, once lubricate oil milky, should replace immediately.


Temperature sensor and vacuum gauge calibrate.


Refrigeration system


  • Filter dryer core regularly inspect and replacement if necessary.
  • Compressor high/low/oil pressure if normal.

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