How to maintain freeze dryer lyophilizers?

How to maintain freeze dryer lyophilizers?

Lubricate oil replacement:   Regular replace vacuum pump oil. First time: 500hrs running. Successive: every 3000hrs.   Regular replace compressor oil. For semi-hermetic compressors. First time: 2000hrs. Successive: every 10000hrs.   Remarks: The labels on vacuum pumps and compressors have guidance of the replacement cycle. Operator need do daily, weekly…
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Vacuum degree, the deeper level the better?

Vacuum degree, the deeper level the better?

  Not always.   Vacuum pumps that installed in freeze drying equipment is not for “Suck” the vapors, its function is maintain the vacuum environment.   The driving force in freeze drying is the vapor pressure difference between the sample temperature and the condenser temperature. The water molecules will move…
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Condenser temperature, the colder the better?

Condenser temperature, the colder the better?

  Not always.   Condenser temperature 10C to 15C colder than sample freezing point is ok. A colder condenser will not speed up the lyophilization, but it will consume more energy, add freeze dry system cost and make your freeze dry system complex.   In another aspect, proper sized condenser…
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